LCMS scientist


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May 24, 2023
Job Type
Start date
Contact Name
Ben Lee
Contact Email


LCMS Scientist

A Global Contract research organisation which is a leading provider of analytical solutions in the biopharmaceutical field, is currently seeking a skilled and knowledgeable LC-MS Scientist to join their esteemed team based in Manchester.

This is an exceptional opportunity for an individual with expertise in LC-HRMS (Liquid Chromatography-High Resolution Mass Spectrometry), along with a strong background in structural biology, to make a significant impact within our organization.

Key Responsibilities:

1. LC-HRMS Expertise: LC-HRMS (Liquid chromatography – High resolution mass spectrometry) instrumentation, data acquisition, analysis and method development will play a pivotal role in advancing our analytical capabilities.

2. Structural Biology Knowledge: Leverage your knowledge of structural biology to interpret LC-MS data within a biopharmaceutical context. By integrating information on protein structure, post-translational modifications, and molecular interactions, you will provide critical insights into the characterization and analysis of complex biomolecules.

3. Application Understanding: Demonstrate a strong understanding of LC-MS applications, including protein and peptide analysis, glycan profiling, metabolomics, and small molecule identification. Your expertise will enable you to design and execute LC-MS experiments tailored to address specific research questions and support drug discovery and development processes.

4. Hands-on Experience: Utilize your extensive hands-on experience in LC-HRMS to perform sample preparation, method development, and instrument operation. You will optimize LC-MS methods, troubleshoot issues, and ensure high-quality and reproducible results in a regulated environment.

5. Quality Assurance: Uphold rigorous quality standards in a GMP and GLP environment, ensuring compliance with regulatory guidelines. Meticulous documentation of experimental protocols, results, and data analysis will be essential to maintaining accuracy and reproducibility.

6. Collaborative Environment: Flourish in a collaborative team environment, collaborating closely with talented scientists, researchers, and analysts. Engage in scientific discussions, share insights, and contribute to a vibrant scientific community focused on advancing the field of analytical sciences.

Qualifications and Skills:

  • Master's or Ph.D. degree in Analytical Chemistry, Structural Biology, or a related field, with a focus on LC-MS.
  • Profound knowledge of LC-HRMS principles, techniques, and instrumentation, with a specific emphasis on its applications in the biopharmaceutical industry.
  • Strong background in structural biology, including an understanding of protein structure, post-translational modifications, and molecular interactions.
  • Hands-on experience in LC-MS method development, sample preparation, and data analysis, preferably in a regulated environment.
  • Proficiency in data interpretation and utilization of relevant software and tools for LC-MS data processing and reporting.
  • Excellent problem-solving skills and the ability to troubleshoot instrument-related issues.
  • Effective communication skills, both written and verbal, enabling clear presentation and documentation of complex scientific concepts.


At this CRO there is a range of scientist positions from associate to Principal and each position offers a competitive compensation packages, continuous professional development opportunities, and a supportive work environment where your contributions are valued and recognized.

If you are ready to embark on an enriching career journey or have any questions about this role apply to this advert with a CV and and I will be in contact.

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